As part of this collaboration, Gene Logic will provide its toxicology databases and data on specific compounds obtained by the company’s gene expression technology for preclinical and clinical research to clients from the pharmaceutical, biotechnology, consumer products and related industries.
With its methodology and expertise in toxicity mechanisms, Genstruct will apply its causal network modeling platform for systems biology to create network models that fully capture the toxicity potential of any compound.
As part of this partnership, Genstruct and Gene Logic will participate in co-marketing initiatives to extend each other’s offerings to current and potential clients. In addition, the companies intend to collaborate in other areas, including personalized or individualized oncology therapy.
Keith Elliston, president and CEO of Genstruct, said: “We are excited by the potential of combining the skill sets of the two companies. In Genstruct’s work with pharmaceutical clients, we have characterized complex and poorly understood mechanisms of toxicity such as idiosyncratic drug-induced liver injury and hemangiosarcoma.
“We can now evaluate a new compound’s potential to elicit these types of reactions in man based on data from simple animal studies. Partnering with a highly regarded data provider like Gene Logic, we can now offer pharmaceutical clients of both companies tremendous additional value in toxicity evaluation.”