So far, the complete set of optimized synthetic human genes sold via Qiagen’s web portal GeneGlobe (QIAgenes) was designed for the production in E coli bacteria only. The new set of genes will now be optimized for the use in insect or mammalian cells.
With this offer, customers from academia as well as from pharmaceutical and biotech companies now can order optimized synthetic genes for use in mammalian and insect cells online via GeneGlobe. All QIAgenes are optimized and synthesized by Geneart.
With QIAgenes the collaboration partners succeeded in making human genes available in a standardized format for scientists all over the world. Customers choose the gene or protein sequence of their choice via the GeneGlobe web portal and receive the corresponding QIAgene by mail.
With this service the marketing of QIAgenes as standardized catalogue product complements Geneart’s existing business to tailor gene sequences for individual customer requests.
Ralf Wagner, CEO and CSO of Geneart, said: “With our GeneOptimizer and GeneAssembler technology we are able to overcome this bottleneck for research. Validation studies have shown that genes optimized and synthesized by Geneart yield up to 50-fold more protein than conventional methods using ‘natural genes’, and achieve high success rates of expression of more than 90%.”