Pharmaceutical Business review

Johnson & Johnson submits NDA for paliperidone

Paliperidone palmitate is a long-acting injectable ester of the active ingredient in Invega which utilizes Elan’s NanoCrystal Technology. If the new drug application (NDA) is approved, paliperidone palmitate will be marketed in the US by Janssen, a subsidiary of Johnson & Johnson dedicated solely to mental health, J&J said.

Schizophrenia is marked by positive symptoms (hallucinations and delusions) and negative symptoms (depression, blunted emotions, and social withdrawal), as well as by disorganized thinking.