According to Seegene, Seeplex MTB ACE provides simple and fast detection in a single multiplex PCR that uses multiple genetic targets – IS6110 and MPB64. The Seeplex MTB ACE detection test uses a single multi-target amplification for specific detection of Mycobacterium tuberculosis (M tuberculosis), and is based on the company’s novel DPO (dual priming oligonucleotides) PCR technology.
IS6110 is the most widely used target gene for detecting M tuberculosis, however; several M tuberculosis strains lack the insertion sequence IS6110. By simultaneously amplifying IS6110 and MPB64, Seeplex MTB ACE is able to identify infections that would otherwise go undiagnosed in a procedure that produces no false positive and false negative results, the company said.
The Seeplex MTB ACE detection detects both extra-pulmonary and pulmonary tuberculosis from various specimens, such as sputum, body fluid, bronchial washing, urine, stool, CSF and bone marrow aspiration. Another important feature of the test is that internal control is co-amplified and co-detected with M tuberculosis, the company added.