The recommended dose of Pristiq (desvenlafaxine) is 50mg once daily. The company has initiated full-scale selling and educational efforts regarding Pristiq for physicians. Dosage adjustment (50mg every other day) is necessary, however, in patients with severe renal impairment or end-stage renal disease.
Philip Ninan, vice president, Wyeth Medical Affairs, Neuroscience, said: “The recommended therapeutic dose of Pristiq is 50mg once daily. Titration is not required to reach the recommended therapeutic dose.”