Under this agreement, AMRI will test samples from its compound collection against several JNK kinases. These kinases may be implicated in the progression of Huntington’s disease (HD). AMRI will use its expertise in computer-aided drug discovery, biological assay development and high throughput screening for this project.
Bruce Sargent, vice president of discovery R&D at AMRI, said: “AMRI is pleased to have this opportunity to partner with CHDI in its efforts to mitigate the effects of HD. We look forward to leveraging our expertise in a broad spectrum of drug discovery services to develop potential treatments for this debilitating condition.
“Based on the potential success of this first phase, AMRI has the ability to provide lead optimization services including medicinal chemistry and in vitro metabolism, making for a fully integrated drug discovery project in terms of time, quality and efficient use of resources.”