According to the companies, the MilliPROBE system is the first solution of its kind for biopharmaceutical manufacturing. It combines Millipore’s sample prep methodologies with Gen-Probe’s advanced nucleic acid technologies to deliver both speed and sensitivity in one microbial screening tool. The MilliPROBE system uses real-time transcription-mediated amplification (TMA) technology to detect targeted microbial contamination within hours compared to the days or weeks usually required to generate results using traditional culture-based technology.
The collaboration’s first MilliPROBE assay targets the bacterium Pseudomonas aeruginosa and is designed as an in-process, early warning system to provide faster, more effective detection of Pseudomonas aeruginosa in purified water used during drug production.