These screens will be used for the in depth evaluation of chemical safety for human health, replacing, reducing or refining animal experiments, and improving the scientific basis of chemical risk assessment.
The NTC will use GeneGo’s MetaCore and MetaDrug systems biology data analysis platform to coordinate, visualize and interpret chemical, metabolomic, proteomic and gene expression data generated by the project members, and to identify the key biological functions and pathways contributing to the adverse effects of xenobiotic exposure.