Out of 146,948 participants, the study identified a total of 413 cases of Parkinson’s disease. The purpose was to identify whether the use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen is associated with a lower risk of Parkinson’s disease.
The findings indicated that ibuprofen users had a 35% lower risk of Parkinson’s disease, and the results were similar in both men and women. The risk also seemed to decrease depending on the weekly dosage. For those taking a daily ibuprofen tablet, the risk was 38% lower, compared to those not regularly taking ibuprofen.
The reason ibuprofen has an effect on the development of Parkinson’s remains unclear and need more research, according to the study researchers. Age, gender, and smoking status – known risk factors for Parkinson’s disease – could not explain the results.
No significant associations were found between the use of aspirin, other NSAIDs, or acetaminophen and the risk of Parkinson’s disease.
The researchers cautioned that the results are preliminary and further study is needed.