Pharmaceutical Business review

FDA lifts clinical hold on YM BioSciences’s pain drug

AeroLEF is being developed as a novel and effective approach to the management of acute pain by delivering a proprietary formulation of inhaled, nebulized, free-and-liposome-encapsulated fentanyl. The free fentanyl results in rapid onset of analgesia while the liposome-encapsulated fentanyl produces the unique extended duration of pain relief, the company said.

YM has also appointed Ali Raza as president of the AeroLEF division to lead the product’s further development. Dr Raza has held a number of leadership roles in established and development-stage pharmaceutical companies. He led the global development of Crestor, a product approved in more than 60 countries and which is competing for market leadership with Lipitor.

David Allan, chairman and CEO of YM, said: “We welcome Dr Raza and have high confidence that his breadth of experience in global drug development will significantly reinforce our team’s ability to realize the substantial value of AeroLEF’s unique approach to the treatment of pain.”