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Novartis extends RNAi therapeutics collaboration with Alnylam

Alnylam Pharmaceuticals has announced that Novartis has elected to extend the company's RNAi therapeutics collaboration for an additional year, through October 2009.

The alliance was initiated in October 2005 and is focused on the discovery, development, and commercialization of RNAi therapeutics toward a defined number of Novartis-selected disease gene targets.

With the extension of the alliance term, Novartis will continue to fund collaboration R&D efforts conducted by Alnylam. Further, Novartis retains its right to exercise a non-exclusive platform license from Alnylam in exchange for an undisclosed payment and future milestones and royalties.

In addition, Novartis has the option to extend the collaboration for one additional one-year term through 2010. Finally, Novartis retains certain rights to purchase Alnylam equity up to 19.9%; current Novartis ownership is approximately 13.4%.