Once issued, this patent will provide protection in Japan until 2029. The claims under the patent cover composition of matter and methods of use for combining Advaxis’s proprietary immunogenic, recombinant tLLO fused to full and partial antigens of particular interest to target cancers such as cervical, ovarian, melanoma, lung, and head and neck.
The antigens covered under the claims include HPV-related and prostate cancer antigens, which are expressed in cervical and prostate cancer. Several of these claims are already patented in the United States. This patent along with the other issued patents in Japan, provides stronger protection for current and future uses of Advaxis immunotherapies.
"The extension of our patent protection to cover composition of matter and methods for our cancer immunotherapies in Japan, demonstrates our commitment to broadly protect our proprietary Lm-LLO technology," said Daniel J. O’Connor, President and Chief Executive Officer of Advaxis.
"This additional patent is important to the future development of our technology as we look to expand our assets into other geographic areas and demonstrates our strong momentum in developing our Lm-LLO platform for multiple cancer indications. Once issued, we will have six patents in Japan."