Vivitrol is a once-monthly, extended-release injectable naltrexone medication, used to treat alcohol dependence and opioid dependence.
As measured by the number of opioid-free urine screens, Vivitrol along with psychosocial treatment, reported prolonged efficacy and safety in a one-year, open-label extension of the six-month pivotal study.
The study also measured opioid craving, improvements in quality of life measures, self-reported opioid use and incidence of physical opioid dependence.