Pharmaceutical Business review

Allele scientists advance human stem cells production technology

The report was published in an article entitled "Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA".

Allele scientists presented the fastest and safest method to convert ordinary human skin cells into "induced pluripotent stem cells" (iPSCs).

The scientific efforts towards this end were led by Allele scientists and Luigi Warren, whose work on "footprint-free" reprogramming using messenger RNA has been the foundation.

The scientists using Warren technique have re-engineered to increase cell conversion efficiency and eliminate any use of potentially unsafe reagents, while substantially reducing the time and effort needed to make stem cells.

Warren said, "Should become the method of choice for iPSC cell banking."

Allele Biotechnology CEO and corresponding author of the paper Jiwu Wang said, "This advance in stem cell derivation will enable both fundamental scientific research and clinical applications which has been the mission of Allele Biotechnology from its inception."