The trial enrolled 73 children with mild to moderate atopic dermatitis into a four-week double-blind period, followed by a four-week open label extension for those patients who wish to continue in the trial.
Topline data from the double blind portion of the trial are expected by end-February, 2015.
"The completion of enrollment of the C012013 Phase II trial represents an important milestone for both the company and the MRX-6 program," said Dr. Gur Roshwalb, Chief Executive Officer of Celsus Therapeutics.
"This trial will provide important insight into the activity of MRX-6 in pediatric atopic dermatitis, and we are thankful for the deep interest and support demonstrated by the parents and children with atopic dermatitis who enrolled in our trial and by our investigators.
"We believe MRX-6 will provide a safe and effective alternative to topical steroids and calcineurin inhibitors for children and adults suffering from atopic dermatitis."
Celsus Therapeutics is an emerging clinical stage company focused on the development of a new class of non-steroidal, synthetic anti-inflammatory drugs termed Multi-Functional Anti-Inflammatory Drugs or MFAIDs. Celsus’s MFAIDs represent a new therapeutic platform for the treatment of a broad array of inflammatory diseases, such as inflammatory and autoimmune diseases.
Presently, the Company’s lead drug candidate in its clinical pipeline is MRX-6, an MFAID topical cream treatment under development for treating skin inflammatory disorders, specifically atopic dermatitis, also known as eczema. Other potential treatments in preclinical development include OPX-1 for ocular inflammation, CFX-1 for cystic fibrosis, and OAX-1 for osteoarthritis.