Benign prostatic hyperplasia (BPH) afflicts approximately half of men over age 50 and close to 90% of men by age 80. The disorder causes difficulties with urination associated with aging, such as urination at night, urge to void frequently, hesitancy, weak stream, and other problems.
The study assessed symptom scores and treatment outcome 8-19 months after NX-1207 treatment. Overall, without further NX-1207 treatment, patients initially treated with NX-1207 showed a total pooled mean improvement of 7.4 points in the primary outcome endpoint of AUA Symptom Score values, which reached statistical significance when compared with the placebo control (p=.028). There have been no significant sexual side effects from NX-1207.
Paul Averback, CEO of Nymox said, “Nymox is continuing to carefully move this drug ahead as rapidly as possible. This placebo-controlled blinded clinical study demonstrates a striking degree of long-term improvement in BPH patients given NX-1207, and confirms the promising results from the earlier completed US clinical trials.”