Pharmaceutical Business review

BMS and Otsuka launch new oral Abilify formulation

Abilify Discmelt (aripiprazole) provides a convenient alternative for adults with schizophrenia or manic episodes associated with bipolar I disorder. Pharmacokinetic studies showed that Abilify Discmelt orally disintegrating tablets are bioequivalent to regular Abilify tablets, thereby offering similar efficacy and safety at the same doses as the oral tablets.

Some adults with schizophrenia or bipolar mania may have difficulty swallowing tablets or, in institutional settings, may hide pills inside their cheek to later spit them out. Abilify Discmelt tablets are placed on the tongue and disintegrate rapidly upon contact with saliva, providing the convenience of a tablet without the need for liquid.

The vanilla-flavored Abilify Discmelt 10mg and 15mg orally disintegrating tablets are packaged in blister packs and each dosage form is colored differently with scattered specks.

“Many adults with schizophrenia or bipolar I disorder, both in inpatient and outpatient settings, don’t take their medication as prescribed,” said Dr John Zajecka, director of the Psychiatry Treatment Research Center and associate professor in the department of psychiatry at Rush University Medical Center in Chicago. “Abilify Discmelt provides healthcare professionals a formulation alternative that may be desirable for some adult patients.”