Pharmaceutical Business review

EC grants approval for Alimta in NSCLC treatment

The European Commission (EC) has granted approval to Eli Lilly and Company for the use of Alimta (pemetrexed for injection) as a single agent for continuation maintenance therapy to treat advanced nonsquamous non-small cell lung cancer (NSCLC).

Clinical trial data which demonstrated an improvement in progression-free survival for NSCLC patients treated first with Alimta plus cisplatin and then with Alimta alone, led to the approval.

Continuation maintenance therapy with Alimta will help in treatment of a particular type of NSCLC, called nonsquamous, and in patients who have shown a positive response or disease stabilization after treatment with first-line Alimta plus cisplatin, the company said.

Lilly Oncology senior medical director Allen Melemed said the approval marks a significant step in the advancement of lung cancer treatment.

"With ALIMTA continuation maintenance therapy, patients with lung cancer who have already benefited from first-line treatment will now have the option to continue treatment with ALIMTA, with the goal of a better clinical outcome," Melemed added.