Pharmaceutical Business review

FDA grants approval for BioMarin facility expansion

According to the company, the facility is expected to support around $1.0bn in revenue for the company’s enzyme replacement therapy portfolio including complex glycoprotein products produced by mammalian cells.

BioMarin CEO Jean-Jacques Bienaime said the approval would support the manufacturing requirements as well as their clinical and pre-clinical programs.

"The facility expansion will also be the initial site of commercial production for GALNS for MPS IVA, if pivotal Phase 3 results are positive in the second half of 2012," Bienaime added.

The manufacturing facility in Novato was first licensed to produce Aldurazyme for MPS I in 2003, then Naglazyme for MPS VI in 2005.