Methazolamide therapy is contraindicated in situations in which sodium and/or potassium serum levels are depressed, in cases of marked kidney or liver disease or dysfunction, in adrenal gland failure, and in hyperchloremic acidosis.
Additionally, long-term administration of Methazolamide is contraindicated in patients with angle-closure glaucoma, since organic closure of the angle may occur in spite of lowered intraocular pressure.
David Cobb, vice president of ophthalmics for Fera, said: “Neptazane represents an alternative to eye drops when IOP is not effectively controlled or patient compliance becomes an issue.”