The biosensor is pre-immobilized with Sigma-Aldrich’s high-affinity ANTI-FLAG M2 antibody, which enables the direct quantitation of FLAG-tagged analytes in crude lysates, column eluents, cell lysates and cell culture supernatants.
Pall’s ForteBio division marketing vice president Christopher Silva said traditional methods for evaluating FLAG-tagged proteins rely on time-consuming, analytical methods, which can slow down drug discovery and development.
"Our new Anti-FLAG Biosensor, together with the BLItz instrument platform’s ease of use or the Octet system’s high throughput, is designed to greatly accelerate laboratory workflow, reduce time to results and increase cost-efficiency," Silva added.
The new biosensor is designed to help the researchers to quickly and easily detect FLAG-tagged recombinant proteins for their quantitation and kinetic characterization, which are key steps in drug development.
ForteBio’s Octet family of products is based on the company’s BioLayer Interferometry technology, which incorporates disposable optical Dip and Read biosensors that measure multiple interactions in parallel, without the use of detection agents.