de Garidel started his career in 1983 with the Eli Lilly pharmaceutical Group where he held various roles, mainly finance related, firstly in France, then in the US and finally in Germany.
In 1995, he joined Amgen, the American biotech Group, as vice president, Finance and Treasury for Europe.
In 1998, he was appointed at Amgen’s headquarters in California as vice president, corporate controller and chief accounting officer.
In 2000, Garidel was offered the role of vice president, general manager for France, in charge of general management of Amgen France.
Garidel also served as president of the Biotech Committee of the French Pharmaceuticals Association (Leem, Les entreprises du medicament) from 2003 to 2006.