Pharmaceutical Business review

Merck, Intercell suspend Phase II/III S aureus vaccine trial

Previously, DMC asked Merck to terminate patient recruitment as the study failed to meet the formal futility criteria.

The decision was based on the data which showed overall mortality and multi-organ dysfunction that occurred with greater frequency in vaccine recipients, compared with placebo recipients.

Further, V710 did not show a statistically significant clinical benefit compared with a placebo.