A single administration of NX-1207 2.5mg has produced on average improvements in the standardised BPH symptom score (8-10 points at 90 days) that were approximately double that reported for currently approved BPH drugs (3-5 points).
The study analysis observed that a statistically significant greater number of men who had received NX-1207 2.5mg reported positive treatment outcomes as compared to men who had received a placebo, with no side effects observed.
The latest available blinded follow-up study data (an average of 57 months post-injection) from the completed trials for the treatment groups were involved in the study.
If the patient was not using other BPH medications and no surgical treatment (including MIST) for BPH was reported at any time during the post-injection follow-up period, a positive treatment outcome was observed.
Previous follow-up studies have shown long-term benefit from a single NX-1207 treatment in excess of five years in some cases.
NX-1207 was found to improve the signs and symptoms of BPH, producing improvements which reached statistical significance compared to double-blinded placebo and study controls in previous studies.