Pharmaceutical Business review

Otsuka, H Lundbeck to develop neuroscience products

The collaboration covers two late stage compounds from Otsuka- aripiprazole depot formulation and OPC-34712.

Aripiprazole depot formulation for schizophrenia is a sterile, lyophilized cake that when reconstituted with sterile water for injection, forms an injectable suspension.

OPC-34712 is a novel investigational psychotherapeutic compound used to treat schizophrenia and major depressive disorder (MDD).

As per the deal, Lundbeck will make an upfront payment upon signing of $200m.

Otsuka will receive around $1.4bn from Lundbeck as upfront payment and development and regulatory milestone payments.

For aripiprazole depot formulation, Lundbeck will receive 50% of net sales in Europe and Canada and 20% of net sales in the US from Otsuka.

In addition, for OPC-34712, Lundbeck will receive 50% of net sales in Europe and Canada and 45% of net sales in the US from Otsuka.