Pharmaceutical Business review

Phytopharm ALS drug obtains Orphan Drug status for amyotrophic lateral sclerosis drug

Cogane is an orally bioavailable neurotrophic factor inducer that crosses the blood-brain barrier and shows neuroprotective effects.

The interim results of Cogane show promising activity in preclinical in vitro and in vivo models of ALS.

The study costs are funded through a UK based charitable organisation – Motor Neurone Disease Association.

A study of Cogane in the genetic in vivo model of ALS is ongoing and the study results are expected in Q4 2011.