Pharmaceutical Business review

PSE Launches gPROMS Solids Process Modelling Environment

PSE said that gPROMS is developed in alignment with Procter & Gamble. gPROMS solids provides an integrated drag and drop graphical flowsheeting environment for model-based engineering and optimisation of solids processes.

PSE stated that the population balance-based models of solids processing equipment are used to validate models against experimental data, optimise process design and operation, determine the optimal process economics and quantify and manage the risks associated with engineering decisions.

PSE claimed that in order to maximise throughput, ensure product quality, size recycles and surge bins for new plants and in general to determine the optimal trade-off between capital and operating cost and make informed purchasing decisions, gPROMS solids helps engineers to optimise the operation of units such as high shear wet granulators, fluidised bed dryers, mills, screens, spray dryers and agglomerators

PSE’s gPROMS solids features include its ability to perform full steady-state modelling, handle large numbers of recycles and model complex operating procedures for batch and semi-continuous processes. It also integrates with gPROMS crystallisation and gas-liquid process models to enable simultaneous whole-process design.

Ben Weinstein, section head of corporate function R&D modeling and simulation at Procter & Gamble, said: “A key advantage of gPROMS solids is that it allows our modellers to develop models of complex processes and apply these to analyse process dynamics.

“Another advantage is the ability to exploit any model using optimisation-based capabilities such as parameter estimation and dynamic optimisation.”

Sean Bermingham, head of consulting at PSE and product manager of gPROMS solids, said: “gPROMS solids provides a flexible platform for integrating companies’ internal R&D and third party research in the future.”