Takeda president and CEO Christophe Weber said: “We are very pleased to have completed the acquisition of Ariad Pharmaceuticals. The addition of Ariad’s innovative targeted therapies and research and development capabilities strengthens and diversifies our oncology business, positioning Takeda for sustainable long-term growth in this priority therapeutic area.
“We are particularly excited by the global potential of brigatinib, an investigational drug product, which we believe will become a best-in-class ALK inhibitor for non-small cell lung cancer with the potential to achieve peak annual sales of over $1bn.
“We are also impressed with the swiftness and agility of Takeda and Ariad employees as they have planned for a successful integration while remaining focused on strategic goals. This bodes very well for the future of our combined business, and we look forward to building on this strong start to maximize the benefit of Iclusig (ponatinib) and potential of brigatinib for cancer patients.”
Takeda Oncology president Christophe Bianchi said: “The acquisition of Ariad is transformational for Takeda Oncology. Iclusig enhances our strong position in hematology in the U.S., and brigatinib has the potential to broaden our solid tumor franchise globally.
“There is a strong cultural fit between our two companies, with a shared mission to advance innovative therapies to improve the lives of patients with cancer. We have been working together over the past month to plan for a smooth integration of our businesses and we will work closely with regulatory authorities on our brigatinib market authorization submissions.”
Takeda continues to expect the transaction to be accretive to Underlying Core Earnings by FY2018. Strong revenue growth and synergy savings will offset increased sales and marketing costs for the anticipated brigatinib launch.
Takeda completed the acquisition through a tender offer and subsequent merger of Ariad with Kiku Merger Co., a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A. Ariad is now an indirect wholly owned subsidiary of Takeda.
The tender offer for all of the outstanding shares of Ariad common stock expired as scheduled, immediately following the offer’s expiration time of 11:59 p.m., Eastern Time, on February 15, 2017. Computershare Trust Company, N.A., the depositary and paying agent for the tender offer, has advised Takeda that 158,558,628 shares of Ariad common stock were tendered, representing approximately 81.4% of the shares outstanding.
All of the conditions to the tender offer having been satisfied, Takeda’s indirect wholly owned subsidiary Kiku Merger Co., Inc. has accepted for payment and will promptly pay for all shares tendered. The transaction will be funded by approximately $3.5bn of new debt and the remainder from existing cash. Takeda is expected to remain investment grade and the transaction has no impact on Takeda’s dividend policy.
On February 16, 2017, Takeda completed its acquisition of Ariad through the merger of Kiku Merger Co., Inc. with Ariad without a vote of Ariad’s shareholders pursuant to Section 251(h) if the Delaware General Corporation Law.
As a result of the merger, Ariad became an indirect wholly owned subsidiary of Takeda. In connection with the merger, all Ariad shares not purchased in the tender offer have been converted into the right to receive $24.00 per share in cash, without interest (less any required withholding taxes), the same amount paid for all shares validly tendered and not validly withdrawn in the tender offer.
Ariad common stock will cease to be traded on the NASDAQ Global Select Market.
Evercore Partners acted as financial advisor and Cleary Gottlieb Steen & Hamilton acted as legal advisor to Takeda. J.P. Morgan Securities, Goldman, Sachs & Co. and Lazard acted as financial advisors and Paul, Weiss, Rifkind, Wharton & Garrison acted as legal advisor to Ariad.