Actos is marketed by Takeda Pharmaceuticals USA and used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes.
According to IMS sales data as of 30 June 2012, the brand product had annual sales of approximately $2.7bn in the US.
Diabetes mellitus type 2 is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency.
The disorder is in contrast to diabetes mellitus type 1 in which there is an absolute insulin deficiency due to destruction of islet cells in the pancreas.