The Automation Partnership (TAP) has reported that its Advanced Projects Group has successfully collaborated with a major European antibody therapeutics company to deliver a custom automated protein purification and concentration system for pre-clinical research.
The company said that the automated protein purification system has been installed and tested and can produce equivalent protein yields to the manual protein processes used previously, with labour.
The walk-away system, designed to purify recombinant proteins from a 50ml sample lysate, includes automated purification via affinity chromatography, buffer exchange, and then protein concentration. The system automatically refrigerates samples overnight, or over the weekend, to maintain quality and allow processing outside working hours. Designed to fit this laboratory’s workflow the system performs two runs every 24 hours, each providing 48 high quality bioassay ready protein samples.
Richard Wales, manager of business development for Advanced Projects’ Group, said: “The group approached us because their major pharma parent had collaborated with TAP and knew we had the capability to design systems which work to their rigorous specifications. The bespoke protein purification system has a very straightforward user interface and includes some clever cost saving features.
“For example, we added three waste units so expensive waste is kept to a minimum. Also, the rack of purification columns can be removed, meaning columns can be regenerated for multiple use. It is this pragmatic eye for details and focus on a simple practical solution to customer’s needs that makes TAP’s Advanced Projects Group such an excellent partner to work with.”