Domainex’s Combinatorial Domain Hunting (CDH) technology is used to identify a form of the MEK protein which can be produced in large quantities and is suitable for structure-based drug discovery.
Domainex research director Trevor Perrior said UCB could successfully utilize the constructs to generate high-resolution structural information and, most importantly, to use it to optimize their chemical series.
Using new structural information, UCB scientists will design a novel class of molecules which inhibit MEK.
Domainex uses unique and proprietary technologies to resolve common bottlenecks facing the pharmaceutical and biotechnology industries in the post-genomic era.