The clinical trial utilized an open-label, Simon two-stage design to evaluate the combination of Zybrestat, carboplatin and paclitaxel in patients with advanced, platinum-resistant ovarian cancer, a refractory form
The Phase IIa randomized, double-blind, proof-of-concept trial will be conducted in multiple European academic medical centers. The trial will evaluate the antiviral activity, pharmacokinetics, safety and tolerability of
The Phase I portion of the trial is designed to determine the dose-limiting toxicity and maximum tolerated dose (MTD) of ispinesib monotherapy administered as a 1-hour intravenous infusion
A total of 24,050,054 shares of Coley common stock were validly tendered and not withdrawn prior to the expiration of the offer, including 661,444 shares subject to guaranteed
The debt is convertible into shares of common stock at $1 per share and the company intends to use the proceeds to fund acquisitions of synergistic companies within
The submission includes efficacy data from two pivotal Phase III trials involving 2,084 patients (1,460 milnacipran, 624 placebo), which showed that milnacipran demonstrated improvement compared to placebo in
Under the terms of the acquisition Hi-Tech receives rights to Midlothian’s current product line, consisting of prescription nutritional supplements including pre-natal vitamins and several cough and cold formulations,
This cooperation will facilitate joint research to investigate the effect of CF102 on hepatitis C virus (HCV) replication in hepatocytes and elucidate the molecular mechanisms underlying the antiviral
The studies, performed in industry-standard rabbit models, indicate that two formulations of Zybrestat, when applied topically to the surface of the eye, are absorbed and result in concentrations
The total enrollment target was comprised of 2,000 normal subjects and 1,400 women with atypical, or Ascus, Pap test results. The next steps in the clinical trial include
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