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Pharmacopeia begins Phase II hypertension study

The objective of the randomized, double-blind, placebo-controlled, parallel-group study is to evaluate PS433540 safety and efficacy in subjects with Stage I and Stage II hypertension. PS433540 is a

AstraZeneca to outsource drug making – report

<p>The Times quoted David Smith, AstraZeneca&#0039;s executive vice-president of operations, as saying that the company aimed to become a pure research, development and marketing organization. <br /><br />According

Hollis-Eden files IND for inflammation drug

Additionally, upon clearance of this IND Hollis-Eden may also consider commencing exploratory studies in the fourth quarter of 2007 to evaluate HE3286 in one or more acute inflammatory

Schering-Plough initiates pivotal HIV drug studies

Vicriviroc is a next-generation extracellular inhibitor of HIV infection designed to block entry of infectious virions into uninfected CD4 cells via antagonism of the CCR5 co-receptor. The vicriviroc

Ligand presents positive preclinical data

LGD-3303 is a selective androgen receptor full agonist in skeletal muscle, a target tissue for androgen action. By comparison, in the prostate and sebaceous glands, the compound is

Microbia and Forest collaborate on IBS drug

Under the terms of the agreement, Forest will initially pay Microbia $70 million in licensing fees. Microbia and Forest will jointly and equally fund development and commercialization of

Metabasis research promising in diabetes

Glucagon is a hormone produced by the pancreas that stimulates the liver to produce glucose (sugar). Overproduction of glucose by the liver is an important cause of high

FDA approves Lilly’s osteoporosis drug Evista

Gwen Krivi, vice president of Lilly research laboratories, said: “The FDA’s decision marks a major milestone. For the first time, postmenopausal women with osteoporosis will have one treatment