Genetic tests become ever more powerful, yet also more complex and costly, which is why it is prudent to include quality control steps throughout the preparation process to ensure the quality of the downstream data obtained.

To make an informed go/no-go decision and avoid analytical failures, a good assessment of the yield and purity of DNA / ribonucleic acid (RNA) isolations is essential, including the detection of carry-over constituents that may interfere with downstream tests.

Here, Trinean validates a novel approach for DNA quality assessment using a large DNA sample set derived from a variety of human tissues combined with a wide scale of extraction methods. This new quality control (QC) tool employs the micro-volume spectroscopy on the DropSense16 ‘Touch & Go’ reader by Trinean combined with its cDrop software to specifically quantify the isolated DNA, as well as identify
each contaminating constituent in the sample contributing to the measured ultraviolet (UV) / visible light (VIS) spectra.