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news.The latest internal review of the currently available safety data from Nymox Pharmaceutical's ongoing phase II trial of NX-1207 for the treatment of benign prostatic hyperplasia has revealed no serious drug side effects.
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NX-1207 has completed two earlier phase I and II trials where the drug produced on average over 23% prostate shrinkage in one month with minimal side effects. Overall there have been no sexual side effects, and a better side effect profile compared to existing drugs.
The symptomatic improvement in earlier trials reached 10 points on the BPH symptom score, which is far superior to available drugs, and compares to invasive and surgical treatments.
On January 23, 2006, an independent data monitoring committee for the trial of NX-1207 gave a positive recommendation based on evaluation of the efficacy and safety data at that point in time.
BPH afflicts approximately half of men over age 50 and close to 90% of men by age 80. The disorder causes difficulties with urination associated with aging, such as urination at night, urge to void frequently, hesitancy, weak stream, and other problems.