Swedish biotech company Cellectricon has formed a collaboration with BioFocus DPI, a UK-based provider of preclinical drug discovery services.
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BioFocus DPI will utilize Cellectricon’s DynaflowHT, a fully automated patch clamp (APC) system, to further increase its electrophysiology-based screening capacity, particularly for fast ligand-gated ion channels, said Cellectricon.
The DynaflowHT microfluidic ion channel screening platform is reported to be the world’s first APC technology enabling high throughput screening of all kinds of ion channels – voltage gated or ligand gated.
According to Cellectricon, fully automated, the DynaflowHT has a throughput exceeding all existing APC systems – at a very competitive running cost. Rapid compound exchange enables highly complex perfusion protocols, gives superior data quality, and reduces compound usage, the company added.
Kate Hilyard, vice president of biological sciences at BioFocus DPI, said: “Cellectricon’s unique high throughput microfluidic screening platform allows us to further develop our leading platform for ion channel screening. This collaboration gives us the opportunity to increase the throughput we provide for customers as well as the number of ion channel subtypes we can screen in an electrophysiology-based format.”
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