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Alvine initiates Phase I trial for celiac disease treatment

Alvine Pharmaceuticals has said that the first study subject was dosed in a single-blind, placebo controlled, dose-escalation Phase I clinical trial of its lead clinical candidate ALV003, which is in development for the treatment of patients with celiac disease.

Approximately 36 subjects are planned for enrollment in the trial to be conducted in the US. Both healthy human volunteers and subjects with celiac disease are expected to be dosed in this trial.