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Invitrogen introduces new microarray for studying non-coding RNA

Invitrogen, a provider of essential life science technologies for research, production and diagnostics, has launched the first high-density microarray for the profiling of non-coding RNAs.

The NCode Human and Mouse non-coding RNA microarrays consist of both non-coding RNA and messenger RNA (mRNA) content on the same array.

According to the company, the NCode non-coding RNA microarrays contain sequences of RNA that do not code for proteins along with sequences of RNA corresponding to mRNAs, which are translated into proteins in a cell. The non-coding sequences were generated and subsequently validated by John Mattick, professor of molecular biology at the University of Queensland, Australia, and his team, and were later exclusively licensed by Invitrogen.

According to the company, the NCode non-coding RNA microarrays include thousands of individual sequences, they must be spotted very densely on a glass slide. To meet this density requirement, Invitrogen partnered with Agilent to use Agilent’s proprietary SurePrint technology to manufacture the NCode non-coding RNA microarrays. Invitrogen will market and distribute the product.

Yvonne Linney, vice president and general manager of genomics at Agilent, said: “The precision and flexibility of Agilent’s SurePrint technology enables an unmatched level of performance and quality that is essential to conduct array-based gene expression research. By selecting SurePrint technology to manufacture this new array for research use, Invitrogen is ensuring the consistent performance of the NCode non-coding microarrays.”