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Marshall Edwards wins IND approval for cancer drug

Marshall Edwards, an oncology company, has received an investigative new drug approval from the FDA to undertake clinical studies with triphendiol as a chemosensitizing agent in combination with gemcitabine.

This approval will enable a Phase Ib study of triphendiol in combination with gemcitabine in patients with unresectable, locally advanced or metastatic pancreatic and bile duct cancers.

Triphendiol (NV-196) is an investigational drug in the Marshall Edwards oncology drug pipeline, currently being developed as an orally-delivered chemosensitizing agent, intended for use in conjunction with standard chemotoxic anticancer drugs for the treatment of late stage pancreatic cancer, cholangiocarcinoma, and melanoma.