Applied Biosystems has developed a sequencing-based molecular tool for the genomic analysis of whole transcriptomes, the vast collection of RNAs transcribed from a genome.
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This technology, which provides detailed characterization of expressed protein-encoding genes, identifies many non-coding RNAs, and includes sample multiplexing capability, is expected to be available for limited release through an early access program that will begin in November 2008.
This offering will expand the company’s RNA expression analysis solutions portfolio for use with its SOLiD system, the company’s ultra-high-throughput genomic analysis platform.
The SOLiD whole transcriptome expression kit is expected to provide researchers greater insights into biological pathways and molecular mechanisms that regulate cell fate decision, development and disease progression.
The kit is said to be designed to provide new views of a cell’s transcriptome, such as expression of non-coding RNAs, identification of alternative splicing events, expressed single nucleotide polymorphisms or mutations, or translocations and fusion transcripts.
Shaf Yousaf, president of molecular and cell biology genomic analysis division at Applied Biosystems, said: “The whole transcriptome kit will follow on the recent launch of the SOLiD small RNA expression kit, providing the company a broad portfolio of tools for analysis of coding and non-coding RNAs on a genomic analysis platform.”
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