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news.Shire has said that its attention deficit hyperactivity disorder patch, Daytrana, still reduces the symptoms of ADHD in children aged six to 12 years when the patch is taken off earlier than the recommended nine hours.
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The phase IIIb trial showed that the patch could offer individualized control over a child’s ADHD symptoms, allowing parents and physicians to better manage the potential for late-day side effects, such as lack of appetite or difficulty sleeping.
Timothy Wilens, associate professor of psychiatry at Harvard Medical School, said: “Because it is a patch, if a child sleeps late on the weekend and the patch is applied later than on a school day, it can still be removed at the usual time. That way, the child receives the benefit of their long-acting ADHD medication for a shorter duration of effect, as well as managing the potential for late-day side effects.
“The physician, in consultation with the parent, can determine the appropriate patch wear time, up to the recommended nine hours.”