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news.Altogen Labs, specialized in providing pre-clinical research services, has launched a new contract research services (CRO) product, small interfering RNA (siRNA) liposome encapsulation.
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The siRNA liposome technique is used in biology laboratories to enable in vivo delivery of siRNA and uses microfluidizer (Microfluidics) technology.
According to the company, in vivo siRNA-induced therapeutic gene silencing (RNAi) is achieved by efficient delivery of small RNA molecules, including siRNA, small hairpin RNA (shRNA), and microRNA (miRNA) into tissues.
In vivo transfection, used to deliver siRNA molecules into animal tissues and tumors in xenograft animal models, helps protect siRNA from degradation in vivo and cross the cellular barriers.
siRNA encapsulation allows efficient and tissue-targeted delivery of small RNAs to animal tissues via multiple administration routes including intravenous, intratumoral, intraperitoneal, intratracheal, intramuscular, oral, or subcutaneous injection, the company said