Advertisement Atlab, BZL Biologics join forces to develop Lu-J591 for cancer treatment - Pharmaceutical Business review
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Atlab, BZL Biologics join forces to develop Lu-J591 for cancer treatment

Atlab Pharma has entered into a sublicense agreement with BZL Biologics for developing 177Lu-J591, a radiopharmaceutical product used to treat cancer.

The agreement comprises exclusive rights to manufacture, develop and commercialize the drug candidate across the globe, besides a joint Phase IIB/III clinical validation program.

In addition, Atlab Pharma will also fund certain product development and clinical trials.

Lu-J591, a tumor-specific delivery system comprises humanized J591 monoclonal antibody targeting prostate-specific membrane antigen (PSMA) in addition to the 177Lu radioisotope.

Phase I and Phase II trials comprising 108 patients with metastatic castrate-resistant prostate cancer, demonstrated efficacy and tolerability of 177Lu -J591.