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Inovio’s partner reports positive HCV vaccine data

Inovio Biomedical's partner, Tripep has reported preliminary results from the first patient to complete treatment with Tripep's therapeutic hepatitis C virus vaccine, ChronVac-C, which was delivered using Inovio's electroporation-based DNA delivery system.

In this Phase I/II clinical study, the treatment has so far been safe and tolerable. Samples taken before, during and after treatment showed that before vaccination the patient did not have a detectable cell-mediated immune response against hepatitis C virus (HCV) but such an immune response became detectable after treatment was completed. Inovio’s electroporation delivery technology is intended to enhance the potency of DNA-based immunotherapies, including DNA vaccines, against cancers and infectious diseases.

Avtar Dhillon, Inovio’s president and CEO, said: “We look forward to seeing additional data, particularly from the higher dose groups, relating to this potential treatment to a pervasive and difficult-to-treat disease.”