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NeurogesX initiates Phase I study of capsaicin liquid formulation

NeurogesX has initiated dosing in its Phase I clinical trial of NGX-1998. The product candidate is a high-concentration, capsaicin-based liquid formulation designed to deliver a localized therapeutic dose directly to the pain site.

The randomized, single-blind Phase I trial is designed to evaluate potential control formulations for future NGX-1998 clinical trials. NeurogesX expects to complete the trial by the end of 2008.

The objective of the NGX-1998 development program is to determine the ability of NGX-1998 to provide protracted pain relief from a single treatment.

Anthony DiTonno, president and CEO of NeurogesX, said: “The initiation of this Phase I trial of NGX-1998 marks a significant step in our program to develop a second-generation liquid formulation of capsaicin to manage pain. We believe that our Phase I trial will provide us with important information that will help shape the design of further studies with the product candidate.”