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Epix terminates depression drug development

Epix Pharmaceuticals has reported that the company is discontinuing clinical development of PRX-00023 due to lack of significant efficacy shown in the recently completed Phase IIb trial in patients with major depressive disorder.

Michael Kauffman, CEO of Epix, said: “While PRX-00023 continued to show a highly desirable safety and tolerability profile, we are disappointed in the overall results observed in our recently completed Phase IIb trial in major depressive disorder. In light of these results, we have made the strategic decision to discontinue further development of this product candidate.”