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news.Oncothyreon has completed the transfer of certain assays and methodology related to Stimuvax, or BLP25 liposome vaccine, to Merck KGaA, Germany, triggering a payment to Oncothyreon of $5 million. The payment will be made under the terms of the amended and restated supply agreement signed in August 2007.
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Stimuvax is an investigational therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a protein antigen widely expressed on common cancers. Merck KGaA currently is conducting a global Phase III trial of Stimuvax in patients with unresectable stage III non-small cell lung cancer (NSCLC).
Robert Kirkman, president and CEO of Oncothyreon, said: “We are pleased with the progress of our collaboration with Merck KGaA for Stimuvax. Stimuvax is an exciting product candidate with promising Phase II data supporting its development as a maintenance therapy after first-line therapy for patients with stage III NSCLC. There are currently no products approved for this indication, which therefore represents both significant unmet medical need and a potentially large market opportunity.”