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Dicerna, Ipsen Collaborate To Develop New Therapeutic Agents In Endocrinology, Oncology

Dicerna Pharmaceuticals (Dicerna) and Ipsen, a global biotechnology specialty care group, have entered into an exclusive research collaboration agreement to leverage their expertise in Dicer Substrate siRNA (DsiRNA) research and peptide engineering.

The companies are expected to develop novel conjugates of Dicerna’s DsiRNA molecules and Ipsen’s peptide targeting vectors in the therapeutic areas of oncology and endocrinology.

James Jenson, co-founder and CEO at Dicerna, said: “The agreement further advances our discovery efforts and provides us with the opportunity to develop Dicer Substrate siRNA therapies and targeted drug delivery systems while working with a partner who brings a unique peptide technology platform to the collaboration.

“This is the second significant partnership with a major biopharmaceutical company that we have entered into in 2010, further validating our next generation Dicer Substrate Technology and our unique ability to generate a greater number of more potent gene silencing molecules.”

Claude Bertrand, EVP and chief scientific officer of Ipsen Group, said: “Combining Dicerna’s Dicer Substrate Technology with Ipsen’s innovative peptide technology that can target specific cell types of interest and mediate intracellular delivery of DsiRNA, will enable us to jointly explore a number of therapeutic programs in the areas of oncology and endocrinology.

“We believe that this collaboration brings together two leading companies with unique and complementary technology platforms which could potentially lead to the discovery of breakthrough DsiRNA-based therapies.”