Biopharmaceutical company Sangart has started testing its lead product, Hemospan, in a single-blind, placebo-controlled Phase II clinical study involving chronic critical limb ischemia patients.
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The study at the Karolinska Institute in Stockholm, Sweden is designed to evaluate the safety and efficacy of Hemospan in patients suffering from chronic critical limb ischemia (CCLI), a debilitating condition that results from severely limited blood circulation to the legs. The primary endpoint is tissue oxygenation measured noninvasively.
Robert Winslow, chairman, president and CEO of Sangart, said: “The goal of this study is to demonstrate that Hemospan can increase oxygen supply to severely compromised tissue, conclusively establishing it as an oxygen-carrying plasma expander.”
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