Viral Genetics reports initial findings from Lyme disease study

Early Lyme disease research has resulted in three significant findings. First, the study team has identified and synthesized ‘key’ peptides that are predicted to have high binding affinity to an individual’s immune cells based on the genetic traits of their immune system.

Secondly, the team has tested the newly identified peptides in mouse models in which the immunological genes are very well characterized. Lastly, the team has shown that the ‘targeted, computationally predicted peptides’ significantly reduce the number and ‘activation state’ of the cells responding to Borrelia proteins.

The study, which was financed by a grant specifically allocated for Lyme disease research, could also potentially offer answers to other immune-based diseases including HIV/AIDS. The team hopes the study will settle the longstanding and controversial debate in the medical community over methods of treatment.

Karen Newell, lead investigator of the study, said: “Our early findings are promising and potentially could unlock the mysteries of Lyme disease as well as other immune-based diseases including HIV/AIDS. We look forward to moving into the clinical phase of research.”